Ichiza lokuQala le-CRISPR liphumelela ukuVunywa kwe-UK kwiSifo seSickle Cell

I-Gen Cutting Edge News

Iindaba ezisandul 'ukuchazwa kwi-GEN (Genetic Engineering & Biotechnology News) zatsho okoabasemagunyeni e-UK banike imvume kwiCasgevy, unyango lwe-CRISPR-Cas9 ngaphambili olwalusaziwa njenge-exa-cel ephuhliswe yi-Vertex Pharmaceuticals kunye ne-CRISPR Therapeutics.Yiisibhengezo esiphawulekayo kwintsimi ye-CRISPR kunye noluntu lwe-sickle cell disease (SCD)..yena US Food and Drug Administration (FDA) kulindeleke ukuba alandele oku kwiiveki ezintathu ezizayo, emva kokuba ekhuphe umhla wesigqibo ngoDisemba 8. Isigqibo esongezelelweyo malunga nonyango lwe-SCD olunxulumene ne-Bluebird bio kufuneka size kamva kuloo nyanga. Imvume yase-UK yabhengezwa yi-arhente yoLawulo lwaMayeza kunye nezeMpilo.ICRISPR-Cas9 iteknolojiuya kunikelaunyango okanye unyango olusebenzayo ngakumbi kwi-sickle cell disease.

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Umfanekiso ovela kwiwebhusayithi yeGenetic Engineering & Biotechnology News

Ulwazi MalungaIrhengqaCellDlula (SCD)

Isifo se-Sickle cell (SCD), ekwaziwa njenge-sickle cell anemia, sisifo sofuzo esichaphazela iiseli ezibomvu zegazi. Yimeko ezuzwe njengelifa ebangelwa kukuguquka kwemfuza ye-HBB, efaka icandelo le-hemoglobin, iprotheni kwiiseli ezibomvu zegazi ezinoxanduva lokuthwala ioksijini kuwo wonke umzimba. Olu tshintsho lukhokelela ekuvelisweni kwehemoglobin engaqhelekanga eyaziwa ngokuba yihemoglobin S (HbS).

Kubantu abanesifo se-sickle cell, i-hemoglobin engaqhelekanga ibangela ukuba iiseli ezibomvu zegazi zibe lukhuni, zinamathele, kunye ne-crescent-shaped (efana ne-sickle). Ezi seli zingaqhelekanga zinokuxinga kwimithambo yegazi emincinci, ekhokelela kwiingxaki ezahlukeneyo, kubandakanya iintlungu, i-anemia, ukonakala kwamalungu, kunye nomngcipheko ophezulu wosulelo.

Indlela elula yokuFumana i-SickleCellDlula

I-Beijing Liuyi Biotechnology Co. Ltd (Liuyi Biotechnology) uye okhethekileyo ekuveliseni izixhobo ze-electrophoresis iminyaka engaphezu kwe-50 kunye neqela lethu lobugcisa lobuchwephesha kunye neziko le-R & D. Sinomgca wemveliso othembekileyo nopheleleyo ukusuka kuyilo ukuya ekuhlolweni, kunye nendawo yokugcina impahla, kunye nenkxaso yokuthengisa. Iimveliso zethu eziphambili ziyi-Electrophoresis Cell (itanki / igumbi), i-Electrophoresis Power Supply, i-Blue LED Transilluminator, i-UV Transilluminator, i-Gel Image & Analysis System njl.

I-Liuyi Bilotechnology yenza imodeli enye yetanki ye-electrophoresis ebizwa ngokuba yi-cellulose acetate membrane elctrophoresis itanki ye-DYCP-38C enokuthi ilungelelaniswe uhlalutyo lweentlobo ze-hemoglobin, kubandakanywa nezo zinxulumene nesifo se-sickle cell (SCD). Yindlela yemveli kunye nezoqoqosho kwi-hemoglobin electrophoresis.

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Ukuba unomdla kule ndlela ilula kunye neyoqoqosho ye-electrophoresis, nceda undwendwele inqaku elilandelayo kwiiprothokholi kunye nezikhokelo ze-hemoglobin electrophoresis ezibonelelwa ngabavavanyi bethu.

Ulingo lokwahlula iprotein yeserum ngeCellulose Acetate Membrane Electrophoresis  

I-Beijing Liuyi biotechnology igxininise ekuveliseni iimveliso ze-electrophoresis iminyaka engaphezu kwe-50 yembali e-China kwaye inkampani inokubonelela ngeemveliso ezizinzileyo neziphezulu kwihlabathi jikelele. Ukutyhubela iminyaka yophuhliso, ilufanele ukhetho lwakho!

Ngoku sikhangela amaqabane, zombini itanki ye-OEM electrophoresis kunye nabasasazi bamkelwe.

Ukuba unayo nayiphi na isicwangciso sokuthenga iimveliso zethu, nceda ungalibazisi ukudibana nathi. Ungasithumela umyalezo nge-imeyile[i-imeyile ekhuselweyo]okanye[i-imeyile ekhuselweyo], okanye nceda usitsalele umnxeba +86 15810650221 okanye wongeze iWhatsapp +86 15810650221, okanye Wechat: 15810650221.

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Iimbekiselo

  1. UkusukaIindaba zobuNjineli beMfuzo kunye neBiyotechnology: Ikhredithi: Artur Plawgo/ Getty Images 

Ixesha lokuposa: Nov-21-2023